Chlorine dioxide-Dossier: Chlorine Dioxide-Short-term toxicity to fish.004

http://www.qsartoolbox.org/de/web/guest/registration-dossier/-/registered-dossier/15450/6/2/2/?documentUUID=1fccbe4d-f0ee-47f9-bc1a-9cca8cae9cf4

Chlorine dioxide

EC number: 233-162-8 | CAS number: 10049-04-4

Administrative data

Purpose flag:

supporting study

Study result type:

experimental result

Reliability:

4 (not assignable)

Data source

Reference

Reference Type:

publication

Title:

Toxicity of chlorien dioxide to early life stages of marine organisms.

Author:

Hose JE, Di Fiore D, Parker HS and Sciarrotta T

Year:

1989

Bibliographic source:

Bull Environ Contam Toxicol, 42: 315-319

Materials and methods

Test guideline

Qualifier:

no guideline followed

Principles of method if other than guideline:

Kelp bass (Serranidae: Paralabrax clathratus) were spawned using 50 µg/kg of luteinising hormone-releasing hormone analog. Eggs were collected and fertilised with stripped milt. They were allowed to settle for 4 hours and the floating viable eggs rinsed several times with filtered seawater. Eggs were maintained at 20°C without aeration. Five chlorine dioxide concentrations were used (2.5 µg/L to 25 µg/L) in addition to the control. Twenty-hour old eggs were stocked into 5 replicate culture dishes contianing 30 mL of solution. Plastic coverswere placed 6 cm above the dishes to keep out dust particles. Bioassay temperature was 20°C. Hatching occurred 40 hours post fertilisation. After 48 hour exposure, dead eggs and larvae and surviving larvae were counted using a dissecting microscope.

GLP compliance:

no

Test materials

Identity of test material same as for substance defined in section 1 (if not read-across):

yes

Test material identityopen allclose all

Test material identity 1

Test material identity 2

Test organisms

Test organisms (species):

other: Paralabrax clathratus

Study design

Total exposure duration:

48 h

Test conditions

Test temperature:

(Monitored at the termination of the bioassay) Within the required limits of APHA (1980): 20oC

pH:

(Monitored at the termination of the bioassay) Within the required limits of APHA (1980).

Dissolved oxygen:

(Monitored at the termination of the bioassay) Within the required limits of APHA (1980).

Salinity:

(Monitored at the termination of the bioassay) Within the required limits of APHA (1980): 33 ppt

Results and discussion

Any other information on results incl. tables:

Table: Effects of chlorine dioxide on early life stages of kelp bass.

Organism	Endpoint	Dose (mg/L)	Response (x + SD (n))
Kelp bass	% survival	0.0000	78.0 ± 7.5 (5)
		0.0025	78.0 ± 14.0 (5)
		0.0250	79.0 ± 12.5 (5)
		0.250	88.0 ± 7.5 (5)
		2.50	87.0 ± 11.5 (5)
		25.0	82.0 ± 17.5 (5)

Applicant's summary and conclusion

Conclusions:

Surivival of larval kelp bass was not significantly affected by chlorine dioxide.